Well, the ancient Egyptians wrote using symbols called hieroglyphs, so they wouldn’t have actually used the letter ‘U’ at all!
However, there are several ancient Egyptian words – mainly names – that begin with U when written using the English alphabet.
Ancient Egpytian Words Beginning With ‘U’
Unas – a pharaoh of the Old Kingdom who ruled during the fifth dynasty
Udjat (also Wedjat) – The Eye of Horus (pictured), which was an amulet and symbol of protection
Upuaut (also Wepwawet) – A canine-shaped Guardian god and war deity (depicted on all fours -unlike Anubis, who was a human with the head of a jackal)
Userkaf – first king to rule during the fifth dynasty
Uto – an Egyptian equivalent of the Greek goddess Leto
As all of these names have been translated from hieroglyphs, there’s no standard spelling for them – their representation isn’t consistent in the heiroglyphs, and the focus is on pronunciation, anyway.